Stabilization of Insulin by Adsorption on a Hydrophobic Silane Self-Assembled Monolayer

The interaction between many proteins and hydrophobic functionalized surfaces is known to induce β-sheet and amyloid fibril formation. In particular, insulin has served as a model peptide to understand such fibrillation, but the early stages of insulin misfolding and the influence of the surface hav...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1999. - 31(2015), 32 vom: 18. Aug., Seite 8892-900
1. Verfasser: Mauri, Sergio (VerfasserIn)
Weitere Verfasser: Volk, Martin, Byard, Stephen, Berchtold, Harald, Arnolds, Heike
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Insulin Proteins Silanes