Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy

Ultrasmall Gold Nanorod Vesicles with Enhanced Tumor Accumulation and Fast Excretion from the Body for Cancer Therapy

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 27(2015), 33 vom: 02. Sept., Seite 4910-7
1. Verfasser: Song, Jibin (VerfasserIn)
Weitere Verfasser: Yang, Xiangyu, Jacobson, Orit, Huang, Peng, Sun, Xiaolian, Lin, Lisen, Yan, Xuefeng, Niu, Gang, Ma, Qingjie, Chen, Xiaoyuan
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't biodegradation nanovesicles photoacoustic imaging photothermal effects ultrasmall gold nanorods Polylactic Acid-Polyglycolic Acid Copolymer 1SIA8062RS Polyglycolic Acid mehr... 26009-03-0 Lactic Acid 33X04XA5AT Polyethylene Glycols 3WJQ0SDW1A Gold 7440-57-5
Beschreibung
Zusammenfassung:© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A new kind of ultrasmall dissociable AuNRPEG/PLGA vesicles (≈60 nm) (AuNR = gold nanorod; PEG = poly(ethylene glycol); PLGA = poly(lactic-co-glycolic acid)) assembled from small AuNRs (dimension: ≈8 nm × 2 nm) is reported. They exhibit several striking features: prolonged circulation and prominent tumor accumulation; rapid excretion from the body as AuNR@PEG after therapy; enhanced photoacoustic and photo thermal properties; and high photothermal cancer therapy efficacy
Beschreibung:Date Completed 31.05.2016
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201502486