Sympathetic Skin Response and Vasomotor Symptoms in Postmenopausal Osteoporotic Women

BACKGROUND: Osteoporosis is a common disease characterized by reduction in bone mass, due to depletion of calcium and bone protein. A pivotal role of the sympathetic nervous system in bone remodeling has been considered. On the other hand, elevated central sympathetic activation in postmenopausal wo...

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Veröffentlicht in:International journal of community based nursing and midwifery. - 2014. - 3(2015), 3 vom: 19. Juli, Seite 227-33
1. Verfasser: Ashraf, Alireza (VerfasserIn)
Weitere Verfasser: Roshanzamir, Sharareh, Bemana, Ghahraman, Mohammadi, Azam, Jahani, Navid, Naseri, Mahshid
Format: Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:International journal of community based nursing and midwifery
Schlagworte:Journal Article Autonomic dysfunction Hot flashes Osteoporosis Sympathetic nervous system
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520 |a BACKGROUND: Osteoporosis is a common disease characterized by reduction in bone mass, due to depletion of calcium and bone protein. A pivotal role of the sympathetic nervous system in bone remodeling has been considered. On the other hand, elevated central sympathetic activation in postmenopausal women is involved in the creation of vasomotor symptoms. Also, sympathetic skin response (SSR) has been performed for evaluation of the peripheral and central autonomic nervous system dysfunctions. Therefore, to determine the association of the autonomic nervous system and osteoporosis, we evaluated the correlation between the bone mineral density (BMD) with the frequency of vasomotor symptoms and also sympathetic skin responses 
520 |a METHODS: This is a cross-sectional study in which thirty-three postmenopausal osteoporosis women, as the case group, and 31 age-matched postmenopausal women with normal BMD, as the control group, were included in our study. To evaluate the autonomic function, we assessed the frequency of vasomotor symptoms with a questionnaire and performed SSR test for the two groups. According to the parametrical or the nonparametrical distribution of the data, Independent Samples t-test or Mann Whitney test, respectively, were used to compare group differences 
520 |a RESULTS: The onset latencies of SSR recorded from both hands and feet were significantly prolonged in the case group compared with the control group (P<0.001). Amplitudes of SSR in the case group were significantly less than those of the control group (P<0.001). The postmenopausal osteoporotic women reported a significantly higher frequency of hot flashes and night sweats when compared with non-osteoporotic women (P<0.001) 
520 |a CONCLUSION: The higher frequency of vasomotor symptoms and impaired sympathetic skin responses in postmenopausal osteoporotic women suggests a role of autonomic dysfunction in osteoporosis 
650 4 |a Journal Article 
650 4 |a Autonomic dysfunction 
650 4 |a Hot flashes 
650 4 |a Osteoporosis 
650 4 |a Sympathetic nervous system 
700 1 |a Roshanzamir, Sharareh  |e verfasserin  |4 aut 
700 1 |a Bemana, Ghahraman  |e verfasserin  |4 aut 
700 1 |a Mohammadi, Azam  |e verfasserin  |4 aut 
700 1 |a Jahani, Navid  |e verfasserin  |4 aut 
700 1 |a Naseri, Mahshid  |e verfasserin  |4 aut 
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