Lithium and Valproate Levels Do Not Correlate with Ketamine's Antidepressant Efficacy in Treatment-Resistant Bipolar Depression

Ketamine and lithium both inhibit glycogen synthase kinase 3. In addition, lithium and ketamine have synergistic antidepressant-like effects at individually subeffective doses in rodents. We hypothesized that ketamine's antidepressant effects would be improved by therapeutic doses of lithium ve...

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Veröffentlicht in:	Neural plasticity. - 1998. - 2015(2015) vom: 07., Seite 858251
1. Verfasser:	Xu, Annie J (VerfasserIn)
Weitere Verfasser:	Niciu, Mark J, Lundin, Nancy B, Luckenbaugh, David A, Ionescu, Dawn F, Richards, Erica M, Vande Voort, Jennifer L, Ballard, Elizabeth D, Brutsche, Nancy E, Machado-Vieira, Rodrigo, Zarate, Carlos A Jr
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2015
Zugriff auf das übergeordnete Werk:	Neural plasticity
Schlagworte:	Journal Article Randomized Controlled Trial Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Antidepressive Agents Valproic Acid 614OI1Z5WI Ketamine 690G0D6V8H Lithium 9FN79X2M3F