The Potential Role of the NLRP3 Inflammasome as a Link between Mitochondrial Complex I Dysfunction and Inflammation in Bipolar Disorder

Mitochondrial dysfunction and activation of the inflammatory system are two of the most consistently reported findings in bipolar disorder (BD). More specifically, altered levels of inflammatory cytokines and decreased levels of mitochondrial complex I subunits have been found in the brain and perip...

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Veröffentlicht in:Neural plasticity. - 1998. - 2015(2015) vom: 01., Seite 408136
1. Verfasser: Kim, Helena Kyunghee (VerfasserIn)
Weitere Verfasser: Chen, Wenjun, Andreazza, Ana Cristina
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Review Carrier Proteins Inflammasomes Inflammation Mediators NLR Family, Pyrin Domain-Containing 3 Protein NLRP3 protein, human Reactive Oxygen Species Electron Transport Complex I EC 7.1.1.2