Post-translational modifications of hormone-responsive transcription factors : the next level of regulation

© The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com.

Bibliographische Detailangaben
Veröffentlicht in:Journal of experimental botany. - 1985. - 66(2015), 16 vom: 04. Aug., Seite 4933-45
1. Verfasser: Hill, Kristine (VerfasserIn)
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Review Auxin signalling DELLA brassinosteroid signalling gibberellin hormone cross-talk post-translational modifications transcription factors transcriptional output. mehr... Brassinosteroids Gibberellins Indoleacetic Acids Plant Growth Regulators Transcription Factors
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520 |a Plants exhibit a high level of developmental plasticity and growth is responsive to multiple developmental and environmental cues. Hormones are small endogenous signalling molecules which are fundamental to this phenotypic plasticity. Post-translational modifications of proteins are a central feature of the signal transduction pathways that regulate gene transcription in response to hormones. Modifications that affect the function of transcriptional regulators may also serve as a mechanism to incorporate multiple signals, mediate cross-talk, and modulate specific responses. This review discusses recent research that suggests hormone-responsive transcription factors are subject to multiple modifications which imply an additional level of regulation conferred by enzymes that mediate specific modifications, such as phosphorylation, ubiquitination, SUMOylation, and S-nitrosylation. These modifications can affect protein stability, sub-cellular localization, interactions with co-repressors and activators, and DNA binding. The focus here is on direct cross-talk involving transcription factors downstream of auxin, brassinosteroid, and gibberellin signalling. However, many of the concepts discussed are more broadly relevant to questions of how plants can modify their growth by regulating subsets of genes in response to multiple cues 
650 4 |a Journal Article 
650 4 |a Review 
650 4 |a Auxin signalling 
650 4 |a DELLA 
650 4 |a brassinosteroid signalling 
650 4 |a gibberellin 
650 4 |a hormone cross-talk 
650 4 |a post-translational modifications 
650 4 |a transcription factors 
650 4 |a transcriptional output. 
650 7 |a Brassinosteroids  |2 NLM 
650 7 |a Gibberellins  |2 NLM 
650 7 |a Indoleacetic Acids  |2 NLM 
650 7 |a Plant Growth Regulators  |2 NLM 
650 7 |a Transcription Factors  |2 NLM 
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