Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation

Discovery of a Novel Polymer for Human Pluripotent Stem Cell Expansion and Multilineage Differentiation

© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Détails bibliographiques
Publié dans:Advanced materials (Deerfield Beach, Fla.). - 1998. - 27(2015), 27 vom: 15. Juli, Seite 4006-12
Auteur principal: Celiz, Adam D (Auteur)
Autres auteurs: Smith, James G W, Patel, Asha K, Hook, Andrew L, Rajamohan, Divya, George, Vinoj T, Flatt, Luke, Patel, Minal J, Epa, Vidana C, Singh, Taranjit, Langer, Robert, Anderson, Daniel G, Allen, Nicholas D, Hay, David C, Winkler, David A, Barrett, David A, Davies, Martyn C, Young, Lorraine E, Denning, Chris, Alexander, Morgan R
Format: Article en ligne
Langue:English
Publié: 2015
Accès à la collection:Advanced materials (Deerfield Beach, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't high throughput human pluripotent stem cells materials discovery polymer microarrays stem cell differentiation Culture Media Polymers
Description
Résumé:© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
A scalable and cost-effective synthetic polymer substrate that supports robust expansion and subsequent multilineage differentiation of human pluripotent stem cells (hPSCs) with defined commercial media is presented. This substrate can be applied to common cultureware and used off-the-shelf after long-term storage. Expansion and differentiation of hPSCs are performed entirely on the polymeric surface, enabling the clinical potential of hPSC-derived cells to be realized
Description:Date Completed 06.04.2016
Date Revised 10.03.2022
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201501351