|
|
|
|
| LEADER |
01000caa a22002652c 4500 |
| 001 |
NLM248980211 |
| 003 |
DE-627 |
| 005 |
20250218125730.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231224s2015 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.3928/23258160-20150422-06
|2 doi
|
| 028 |
5 |
2 |
|a pubmed25n0829.xml
|
| 035 |
|
|
|a (DE-627)NLM248980211
|
| 035 |
|
|
|a (NLM)25970864
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Salz, David A
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Oral eplerenone for treatment of chronic central serous chorioretinopathy
|b a case series
|
| 264 |
|
1 |
|c 2015
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 23.10.2015
|
| 500 |
|
|
|a Date Revised 10.04.2022
|
| 500 |
|
|
|a published: Print
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Copyright 2015, SLACK Incorporated.
|
| 520 |
|
|
|a BACKGROUND AND OBJECTIVE: To evaluate the effect of oral eplerenone on subretinal fluid, visual acuity, and choroidal thickness in patients with chronic central serous chorioretinopathy (CSCR)
|
| 520 |
|
|
|a PATIENTS AND METHODS: Retrospective review of all patients (14 eyes of 14 patients) monitored for a minimum of 3 months with chronic CSCR who were treated with oral eplerenone in a single multi-physician retina practice. Visual acuity, dilated funduscopic examination, and spectral-domain ocular coherence tomography (OCT) with enhanced depth imaging (EDI) were obtained at each visit. Measurement of subfoveal fluid (SFF) height and choroidal thickness were performed. Two-tailed paired t test was used to calculate statistical significance of pre- and post-treatment variables
|
| 520 |
|
|
|a RESULTS: At 1 month, 10 of 14 eyes had decreased SFF height on OCT and two eyes had complete resolution of SFF. Mean SFF height decreased from 130 µm to 62 µm (P = .05). Mean choroidal thickness decreased from 315 µm to 282 µm (P = .07). Mean visual acuity improved from logMAR 0.41 to 0.40. At 3 months, 13 of 14 (93%) had decreased SFF on OCT, and nine eyes (64%) had complete resolution of SFF. Mean SFF height decreased to 21 µm (P = .004). Mean choroidal thickness decreased to 253 µm (P = .10). Mean visual acuity improved to logMAR 0.28 (P = .02)
|
| 520 |
|
|
|a CONCLUSION: Oral eplerenone may be effective in treating patients with chronic CSCR
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
7 |
|a Mineralocorticoid Receptor Antagonists
|2 NLM
|
| 650 |
|
7 |
|a Spironolactone
|2 NLM
|
| 650 |
|
7 |
|a 27O7W4T232
|2 NLM
|
| 650 |
|
7 |
|a Eplerenone
|2 NLM
|
| 650 |
|
7 |
|a 6995V82D0B
|2 NLM
|
| 700 |
1 |
|
|a Pitcher, John D
|c 3rd
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Hsu, Jason
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Regillo, Carl D
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Fineman, Mitchell S
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Elliott, Kevin S
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Vander, James F
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Fischer, David H
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Spirn, Marc J
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 46(2015), 4 vom: 13. Apr., Seite 439-44
|w (DE-627)NLM224956647
|x 2325-8179
|7 nnas
|
| 773 |
1 |
8 |
|g volume:46
|g year:2015
|g number:4
|g day:13
|g month:04
|g pages:439-44
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.3928/23258160-20150422-06
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_11
|
| 912 |
|
|
|a GBV_ILN_24
|
| 912 |
|
|
|a GBV_ILN_31
|
| 912 |
|
|
|a GBV_ILN_40
|
| 912 |
|
|
|a GBV_ILN_63
|
| 912 |
|
|
|a GBV_ILN_65
|
| 912 |
|
|
|a GBV_ILN_69
|
| 912 |
|
|
|a GBV_ILN_70
|
| 912 |
|
|
|a GBV_ILN_90
|
| 912 |
|
|
|a GBV_ILN_91
|
| 912 |
|
|
|a GBV_ILN_130
|
| 912 |
|
|
|a GBV_ILN_135
|
| 912 |
|
|
|a GBV_ILN_136
|
| 912 |
|
|
|a GBV_ILN_151
|
| 912 |
|
|
|a GBV_ILN_181
|
| 912 |
|
|
|a GBV_ILN_203
|
| 912 |
|
|
|a GBV_ILN_217
|
| 912 |
|
|
|a GBV_ILN_235
|
| 912 |
|
|
|a GBV_ILN_289
|
| 912 |
|
|
|a GBV_ILN_294
|
| 912 |
|
|
|a GBV_ILN_297
|
| 912 |
|
|
|a GBV_ILN_350
|
| 912 |
|
|
|a GBV_ILN_352
|
| 912 |
|
|
|a GBV_ILN_674
|
| 912 |
|
|
|a GBV_ILN_676
|
| 912 |
|
|
|a GBV_ILN_688
|
| 912 |
|
|
|a GBV_ILN_698
|
| 912 |
|
|
|a GBV_ILN_721
|
| 912 |
|
|
|a GBV_ILN_737
|
| 912 |
|
|
|a GBV_ILN_791
|
| 912 |
|
|
|a GBV_ILN_812
|
| 912 |
|
|
|a GBV_ILN_1127
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 46
|j 2015
|e 4
|b 13
|c 04
|h 439-44
|