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231224s2015 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201500762
|2 doi
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|a eng
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| 100 |
1 |
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|a Tseng, Ting-Chen
|e verfasserin
|4 aut
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| 245 |
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|a An Injectable, Self-Healing Hydrogel to Repair the Central Nervous System
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|c 2015
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 11.03.2016
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a An injectable, self-healing hydrogel (≈1.5 kPa) is developed for healing nerve-system deficits. Neurosphere-like progenitors proliferate in the hydrogel and differentiate into neuron-like cells. In the zebrafish injury model, the central nervous system function is partially rescued by injection of the hydrogel and significantly rescued by injection of the neurosphere-laden hydrogel. The self-healing hydrogel may thus potentially repair the central nervous system
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a injectable hydrogels
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|a neural repair
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|a neural stem cells
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|a self-healing polymers
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|a Alginates
|2 NLM
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|a Biocompatible Materials
|2 NLM
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| 650 |
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|a Hexuronic Acids
|2 NLM
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| 650 |
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|a Hydrogel, Polyethylene Glycol Dimethacrylate
|2 NLM
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| 650 |
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|a 25852-47-5
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|a Glucuronic Acid
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|a Chitosan
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7 |
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| 700 |
1 |
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|a Tao, Lei
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|a Hsieh, Fu-Yu
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| 700 |
1 |
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|a Wei, Yen
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chiu, Ing-Ming
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Hsu, Shan-hui
|e verfasserin
|4 aut
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|t Advanced materials (Deerfield Beach, Fla.)
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|g 27(2015), 23 vom: 17. Juni, Seite 3518-24
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