Enantiospecific Adsorption of Amino Acids on Naturally Chiral Cu{3,1,17}R&S Surfaces
Gas-phase equilibrium adsorption of D- and L-serine (Ser) mixtures and D- and L-phenylalanine (Phe) mixtures has been studied on the naturally chiral Cu{3,1,17}(R&S) surfaces. (13)C labeling of the l enantiomers (*L-Ser and *L-Phe) has enabled mass spectrometric enantiodiscrimination of the spec...
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 31(2015), 22 vom: 09. Juni, Seite 6055-63 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2015
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids |
| Schlagworte: | Journal Article Research Support, U.S. Gov't, Non-P.H.S. Amino Acids Copper 789U1901C5 |
| Zusammenfassung: | Gas-phase equilibrium adsorption of D- and L-serine (Ser) mixtures and D- and L-phenylalanine (Phe) mixtures has been studied on the naturally chiral Cu{3,1,17}(R&S) surfaces. (13)C labeling of the l enantiomers (*L-Ser and *L-Phe) has enabled mass spectrometric enantiodiscrimination of the species desorbing from the surface following equilibrium adsorption. On the Cu{3,1,17}(R&S) surfaces, both equilibrium adsorption and the thermal decomposition kinetics of the D and *L enantiomers exhibit diastereomerism. Following exposure of the surfaces to D/*L mixtures, the relative equilibrium coverages of the two enantiomers are equal to their relative partial pressures in the gas phase, θ(D)/θ(*L) = P(D)/P(*L). This implies that adsorption is not measurably enantiospecific. The decomposition kinetics of Ser are enantiospecific whereas those of Phe are not. Comparison of these results with those for aspartic acid, alanine, and lysine suggests that enantiospecific adsorption on the naturally chiral Cu surfaces occurs for those amino acids that have side chains with functional groups that allow strong interactions with the surface. There is no apparent correlation between amino acids that exhibit enantiospecific adsorption and those that exhibit enantiospecific decomposition kinetics |
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| Beschreibung: | Date Completed 09.03.2016 Date Revised 09.06.2015 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1520-5827 |
| DOI: | 10.1021/acs.langmuir.5b00707 |