Effects of norfloxacin on hepatic genes expression of P450 isoforms (CYP1A and CYP3A), GST and P-glycoprotein (P-gp) in Swordtail fish (Xiphophorus Helleri)

The presence of antibiotics including norfloxacin in the aquatic environment may cause adverse effects in non-target organisms. But the toxic mechanisms of fluoroquinolone to fish species are still not completely elucidated. Thus, it is essential to investigate the response of fish to the exposure o...

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Veröffentlicht in:Ecotoxicology (London, England). - 1992. - 24(2015), 7-8 vom: 20. Okt., Seite 1566-73
1. Verfasser: Liang, Ximei (VerfasserIn)
Weitere Verfasser: Wang, Lan, Ou, Ruikang, Nie, Xiangping, Yang, YuFeng, Wang, Fang, Li, Kaibin
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Ecotoxicology (London, England)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Enzyme activity Gene expression Norfloxacin Sub-chronic toxicity Swordtail fish (Xiphophorus helleri) Anti-Bacterial Agents Fish Proteins RNA, Messenger mehr... Water Pollutants, Chemical N0F8P22L1P