Comparative analysis of T4 DNA ligases and DNA polymerases used in chromosome conformation capture assays

Three-dimensional (3-D) genome organization in the nuclear space affects various genomic functions. Circular chromosome conformation capture (4C-seq) is a powerful technique that allows researchers to measure long-range chromosomal interactions with a locus of interest across the entire genome. This...

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Détails bibliographiques
Publié dans:BioTechniques. - 1991. - 58(2015), 4 vom: 15. Apr., Seite 195-9
Auteur principal: Schwartz, Michal (Auteur)
Autres auteurs: Sarusi, Avital, Deitch, Rachel T, Tal, Moran, Raz, Dana, Sung, Myong-Hee, Kaplan, Tommy, Hakim, Ofir
Format: Article en ligne
Langue:English
Publié: 2015
Accès à la collection:BioTechniques
Sujets:Comparative Study Journal Article Research Support, Non-U.S. Gov't 3C 4C chromosome conformation capture nuclear architecture Cross-Linking Reagents DNA-Directed DNA Polymerase EC 2.7.7.7 plus... DNA Ligases EC 6.5.1.-