Nanopore Analysis of Single-Stranded Binding Protein Interactions with DNA
We study the binding of E. coli single-stranded binding protein (SSB) to single-stranded DNA (ssDNA) using a solid-state nanopore assay. We find that saturated nucleoprotein complexes can be distinguished easily from free SSB, ssDNA, or double-stranded DNA individually and demonstrate that the high...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1999. - 31(2015), 15 vom: 21. Apr., Seite 4582-8
|
1. Verfasser: |
Marshall, Michael M
(VerfasserIn) |
Weitere Verfasser: |
Ruzicka, Jan,
Zahid, Osama K,
Henrich, Vincent C,
Taylor, Ethan W,
Hall, Adam R |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2015
|
Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
|
Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
DNA, Single-Stranded
DNA-Binding Proteins
Escherichia coli Proteins
Nucleoproteins |