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20231224143520.0 |
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231224s2015 xx |||||o 00| ||eng c |
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|a 10.1007/s10646-015-1434-8
|2 doi
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|a pubmed24n0822.xml
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|a (DE-627)NLM246645156
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|a (NLM)25725815
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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1 |
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|a Alvarado-Flores, Jesús
|e verfasserin
|4 aut
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| 245 |
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|a Morphological alterations in the freshwater rotifer Brachionus calyciflorus Pallas 1766 (Rotifera
|b Monogononta) caused by vinclozolin chronic exposure
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| 264 |
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|c 2015
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 22.12.2015
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|a Date Revised 30.09.2020
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Vinclozolin (VZ) is a dicarboximide fungicide widely used on fruits, vegetables and wines, effective against fungi plagues. In this study we characterized the effects of VZ using a 4-day reproductive chronic assay with the freshwater rotifer Brachionus calyciflorus. The assay included observations of several features of asexual and sexual reproduction. Our results indicate that VZ: (a) increased asexual and sexual reproduction, (b) caused severe abnormality in females and (c) these abnormalities were inherited by sexual and asexual reproduction. At 1.2 mg/L three abnormal females were found out of 457 total females (0.66 %). This low percentage is consistent and reproducible according to further analysis, where we increased the number of replicates and total females exposed to 1.2 mg/L of VZ, and found 18 abnormal females out of 2868 total females (0.63 % abnormality). Interestingly, abnormal females found at 5.6 mg/L VZ exposure, were able to show mating behavior. Our results suggest that VZ behaves as a strong endocrine disruptor whose effects show the characteristic inverted-U-shape exposure concentration response curve regarding the intrinsic population increase and the percentage of abnormalities as endpoints
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|a Journal Article
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| 650 |
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|a Research Support, Non-U.S. Gov't
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| 650 |
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7 |
|a Endocrine Disruptors
|2 NLM
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| 650 |
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7 |
|a Fungicides, Industrial
|2 NLM
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| 650 |
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7 |
|a Oxazoles
|2 NLM
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| 650 |
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|a Water Pollutants, Chemical
|2 NLM
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| 650 |
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7 |
|a vinclozolin
|2 NLM
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| 650 |
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7 |
|a JJ258EZN1I
|2 NLM
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| 700 |
1 |
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|a Rico-Martínez, Roberto
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Adabache-Ortíz, Araceli
|e verfasserin
|4 aut
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| 700 |
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|a Silva-Briano, Marcelo
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Ecotoxicology (London, England)
|d 1992
|g 24(2015), 4 vom: 28. Mai, Seite 915-25
|w (DE-627)NLM098212214
|x 1573-3017
|7 nnns
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| 773 |
1 |
8 |
|g volume:24
|g year:2015
|g number:4
|g day:28
|g month:05
|g pages:915-25
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| 856 |
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|u http://dx.doi.org/10.1007/s10646-015-1434-8
|3 Volltext
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