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01000caa a22002652 4500 |
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NLM245637400 |
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DE-627 |
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20250218023314.0 |
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tu |
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231224s2014 xx ||||| 00| ||chi c |
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|a pubmed25n0818.xml
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|a (NLM)25619345
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a chi
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| 100 |
1 |
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|a Tang, Xiaolei
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Clinical characteristics of children with Langerhans cell histiocytosis with pulmonary involvement
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| 264 |
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1 |
|c 2014
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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| 500 |
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|a Date Completed 30.03.2015
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|a Date Revised 02.12.2018
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a OBJECTIVE: To improve the recognition of the clinical presentation and radiologic manifestation of children with Langerhans cell histiocytosis (LCH) with pulmonary involvement
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| 520 |
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|a METHOD: A retrospective analysis was conducted on children who presented with respiratory symptoms or abnormal lung radiologic findings, and finally diagnosed with LCH in Ward 2 of Divison of Respiratory Diseases, Beijing Children's Hospital during the last 4 years
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| 520 |
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|a RESULT: Fourteen children (10 boys and 4 girls) were included in this study. Male to female ratio was 2.5: 1. The median age was 1.3 years. Pulmonary involvements were coexisted with other involved organs in all the patients, such as skin (10 cases, 71%), liver (8 cases, 57%), and bone involvement (7 cases, 50%). The most common symptoms were cough and fever (7 cases, 50%). Respiratory symptoms were nonspecific, and 3 children had no respiratory symptom but abnormal findings on lung high-resolution CT (HRCT). The most common HRCT finding was the coexistence of nodules and cysts (6 cases, 43%). Other findings include cysts only (5 cases, 36%), nodules only (1 case), and with neither nodule nor cyst (2 cases, 14%). Pneumothorax was found in 7% of children
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| 520 |
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|a CONCLUSION: Pulmonary involvement in children with LCH is easily misdiagnosed, and often coexisted with other involved tissues/organs such as skin and liver. Rash, which is easily missed in physical examination is very important for the diagnosis of LCH. The characteristic findings of lung HRCT (nodules and/or cysts) are helpful for diagnosis
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| 650 |
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|a Journal Article
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| 700 |
1 |
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|a Wang, Wei
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liu, Jinrong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yang, Haiming
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhao, Shunying
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Li, Huimin
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Zhonghua er ke za zhi = Chinese journal of pediatrics
|d 1960
|g 52(2014), 12 vom: 14. Dez., Seite 902-5
|w (DE-627)NLM136249191
|x 0578-1310
|7 nnns
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| 773 |
1 |
8 |
|g volume:52
|g year:2014
|g number:12
|g day:14
|g month:12
|g pages:902-5
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