Modulation of charge transport across double-stranded DNA by the site-specific incorporation of copper bis-phenanthroline complexes

Modulation of charge transport across double-stranded DNA by the site-specific incorporation of copper bis-phenanthroline complexes

The site-specific incorporation of transition-metal complexes within DNA duplexes, followed by their immobilization on a gold surface, was studied by electrochemistry to characterize their ability to mediate charge. Cyclic voltammetry, square-wave voltammetry, and control experiments were carried ou...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 31(2015), 5 vom: 10. Feb., Seite 1850-4
1. Verfasser: Dauphin-Ducharme, Philippe (VerfasserIn)
Weitere Verfasser: Rosati, Fiora, Greschner, Andrea, De Bruijn, A Dowine, Salvatore, Danielle, Toader, Violeta, Lau, Kai Lin, Mauzeroll, Janine, Sleiman, Hanadi
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Organometallic Compounds Phenanthrolines DNA 9007-49-2 1,10-phenanthroline W4X6ZO7939
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520 |a The site-specific incorporation of transition-metal complexes within DNA duplexes, followed by their immobilization on a gold surface, was studied by electrochemistry to characterize their ability to mediate charge. Cyclic voltammetry, square-wave voltammetry, and control experiments were carried out on fully matched and mismatched DNA strands that are mono- or bis-labeled with transition-metal complexes. These experiments are all consistent with the ability of the metal centers to act as a redox probe that is well coupled to the DNA π-stack, allowing DNA-mediated charge transport 
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700 1 |a Greschner, Andrea  |e verfasserin  |4 aut 
700 1 |a De Bruijn, A Dowine  |e verfasserin  |4 aut 
700 1 |a Salvatore, Danielle  |e verfasserin  |4 aut 
700 1 |a Toader, Violeta  |e verfasserin  |4 aut 
700 1 |a Lau, Kai Lin  |e verfasserin  |4 aut 
700 1 |a Mauzeroll, Janine  |e verfasserin  |4 aut 
700 1 |a Sleiman, Hanadi  |e verfasserin  |4 aut 
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