TAL effectors--pathogen strategies and plant resistance engineering

Transcription activator-like effectors (TALEs) from plant pathogenic Xanthomonas spp. and the related RipTALs from Ralstonia solanacearum are DNA-binding proteins with a modular DNA-binding domain. This domain is both predictable and programmable, which simplifies elucidation of TALE function in pla...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1979. - 204(2014), 4 vom: 19. Dez., Seite 823-32
1. Verfasser: Boch, Jens (VerfasserIn)
Weitere Verfasser: Bonas, Ulla, Lahaye, Thomas
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Review Fungal Proteins Plant Proteins Transcription Factors
LEADER 01000naa a22002652 4500
001 NLM24486943X
003 DE-627
005 20231224135628.0
007 cr uuu---uuuuu
008 231224s2014 xx |||||o 00| ||eng c
028 5 2 |a pubmed24n0816.xml 
035 |a (DE-627)NLM24486943X 
035 |a (NLM)25539004 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Boch, Jens  |e verfasserin  |4 aut 
245 1 0 |a TAL effectors--pathogen strategies and plant resistance engineering 
264 1 |c 2014 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 15.05.2016 
500 |a Date Revised 30.09.2020 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a Transcription activator-like effectors (TALEs) from plant pathogenic Xanthomonas spp. and the related RipTALs from Ralstonia solanacearum are DNA-binding proteins with a modular DNA-binding domain. This domain is both predictable and programmable, which simplifies elucidation of TALE function in planta and facilitates generation of DNA-binding modules with desired specificity for biotechnological approaches. Recently identified TALE host target genes that either promote or stop bacterial disease provide new insights into how expression of TALE genes affects the plant–pathogen interaction. Since its elucidation the TALE code has been continuously refined and now provides a mature tool that, in combination with transcriptome profiling, allows rapid isolation of novel TALE target genes. The TALE code is also the basis for synthetic promoter-traps that mediate recognition of TALE or RipTAL proteins in engineered plants. In this review, we will summarize recent findings in plant-focused TALE research. In addition, we will provide an outline of the newly established gene isolation approach for TALE or RipTAL host target genes with an emphasis on potential pitfalls 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Review 
650 7 |a Fungal Proteins  |2 NLM 
650 7 |a Plant Proteins  |2 NLM 
650 7 |a Transcription Factors  |2 NLM 
700 1 |a Bonas, Ulla  |e verfasserin  |4 aut 
700 1 |a Lahaye, Thomas  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t The New phytologist  |d 1979  |g 204(2014), 4 vom: 19. Dez., Seite 823-32  |w (DE-627)NLM09818248X  |x 1469-8137  |7 nnns 
773 1 8 |g volume:204  |g year:2014  |g number:4  |g day:19  |g month:12  |g pages:823-32 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 204  |j 2014  |e 4  |b 19  |c 12  |h 823-32