Degradation of antidepressant drug fluoxetine in aqueous media by ozone/H2O2 system : process optimization using central composite design
The main objective of this work is the modelling and optimization of antidepressant drug fluoxetine degradation in aqueous solution by ozone/H2O2 process using central composite design. The operational parameters were ozone concentration, initial hydrogen peroxide concentration, reaction time and in...
| Veröffentlicht in: | Environmental technology. - 1998. - 36(2015), 9-12 vom: 10. Mai, Seite 1477-88 |
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| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2015
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| Zugriff auf das übergeordnete Werk: | Environmental technology |
| Schlagworte: | Evaluation Study Journal Article central composite design fluoxetine ozonation pharmaceutical wastewater response surface methodology Water Pollutants, Chemical Fluoxetine 01K63SUP8D mehr... |
| Zusammenfassung: | The main objective of this work is the modelling and optimization of antidepressant drug fluoxetine degradation in aqueous solution by ozone/H2O2 process using central composite design. The operational parameters were ozone concentration, initial hydrogen peroxide concentration, reaction time and initial fluoxetine concentration. A good agreement between the predicted values of fluoxetine removal and experimental results were observed (R2=0.976 and Adj-R2=0.955). Pareto analysis indicated that all selected factors and some interactions were effective on the removal efficiency. It was found that the reaction time is the most effective parameter in the ozone/H2O2 process. The maximum removal efficiency (86.14%) was achieved at ozone concentration of 30 mg L(-1), initial H2O2 concentration of 0.02 mM, reaction time of 20 min and initial fluoxetine concentration of 50 mg L(-1) as the optimum conditions |
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| Beschreibung: | Date Completed 01.10.2015 Date Revised 10.12.2019 published: Print Citation Status MEDLINE |
| ISSN: | 0959-3330 |
| DOI: | 10.1080/09593330.2014.994041 |