Amphipathic membrane-active peptides recognize and stabilize ruptured membrane pores : exploring cause and effect with coarse-grained simulations

Induction of membrane pores has been suggested as the common molecular action by which a variety of amphipathic membrane-active peptides cause damage to cells. In this study, we have performed coarse-grained molecular dynamics simulations to establish two clear molecular processes that seem critical...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1999. - 31(2015), 2 vom: 20. Jan., Seite 752-61
1. Verfasser: Sun, Delin (VerfasserIn)
Weitere Verfasser: Forsman, Jan, Woodward, Clifford E
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Lipid Bilayers Peptides