Ursolic acid incorporation does not prevent the formation of a non-lamellar phase in pH-sensitive and long-circulating liposomes

Ursolic acid (UA) is a triterpene found in different plant species that has been shown to possess significant antitumor activity. However, UA presents a low water solubility, which limits its biological applications. In this context, our research group has proposed the incorporation of UA in long-ci...

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Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1985. - 30(2014), 50 vom: 23. Dez., Seite 15083-90
1. Verfasser:	Lopes, Sávia C A (VerfasserIn)
Weitere Verfasser:	Novais, Marcus V M, Ferreira, Diêgo S, Braga, Fernão C, Magalhães-Paniago, Rogério, Malachias, Ângelo, Oliveira, Mônica C
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2014
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't 1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine Buffers Cholesterol Esters Liposomes Phosphates Phosphatidylethanolamines Triterpenes 1,2-distearoylphosphatidylethanolamine mehr... 1G4B5265CQ Polyethylene Glycols 3WJQ0SDW1A cholesteryl succinate T3J4KS4201