Impact of polymer conformation on the crystal growth inhibition of a poorly water-soluble drug in aqueous solution

Poor aqueous solubility is a major hindrance to oral delivery of many emerging drugs. Supersaturated drug solutions can improve passive absorption across the gastrointestinal tract membrane as long as crystallization can be inhibited, enhancing the delivery of such poorly soluble therapeutics. Polym...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 31(2015), 1 vom: 08., Seite 171-9
1. Verfasser: Schram, Caitlin J (VerfasserIn)
Weitere Verfasser: Beaudoin, Stephen P, Taylor, Lynne S
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2015
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Polymers Water 059QF0KO0R Felodipine OL961R6O2C