Adsorption-induced changes in ribonuclease A structure and enzymatic activity on solid surfaces

Ribonuclease A (RNase A) is a small globular enzyme that lyses RNA. The remarkable solution stability of its structure and enzymatic activity has led to its investigation to develop a new class of drugs for cancer chemotherapeutics. However, the successful clinical application of RNase A has been re...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 30(2014), 49 vom: 16. Dez., Seite 14849-58
1. Verfasser: Wei, Yang (VerfasserIn)
Weitere Verfasser: Thyparambil, Aby A, Wu, Yonnie, Latour, Robert A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Silicon Dioxide 7631-86-9 Ribonuclease, Pancreatic EC 3.1.27.5