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231224s2015 xx |||||o 00| ||eng c |
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|a 10.1093/jxb/eru444
|2 doi
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|a pubmed25n0812.xml
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|a (DE-627)NLM243603894
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|a (NLM)25403917
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Strohm, Allison K
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Natural variation in the expression of ORGANIC CATION TRANSPORTER 1 affects root length responses to cadaverine in Arabidopsis
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|c 2015
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 08.03.2016
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|a Date Revised 13.11.2018
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|a published: Print-Electronic
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|a GEO: GSE28275
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|a Citation Status MEDLINE
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|a © The Author 2014. Published by Oxford University Press on behalf of the Society for Experimental Biology.
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|a Polyamines, including cadaverine, are organic cations that affect numerous biological processes including transcription, translation, cell signalling, and ion channel activity. They often function in biotic and abiotic stress responses in plants. Because little is known about how plants respond to cadaverine, a quantitative natural variation approach was used to identify genetic factors that contribute to this response. Here it is shown that Arabidopsis thaliana accessions have varying root length responses to exogenous cadaverine: Cape Verde Islands (Cvi) was one of the most resistant accessions tested, whereas Landsberg erecta (Ler) was one of the most sensitive. Recombinant inbred lines, near isogenic lines, and a microarray were used to show that variation in ORGANIC CATION TRANSPORTER 1 (OCT1) is at least partially responsible for this difference. OCT1 expression was higher in Cvi than in Ler, and oct1 mutants were more sensitive to cadaverine than wild-type plants. In oct1 mutants transformed with an ectopic copy of OCT1 originating from either Cvi or Ler, the expression level of the transgene, not its accession, correlated with the cadaverine response. These results suggest that decreased OCT1 expression confers cadaverine sensitivity in some accessions
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|a Journal Article
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|a Research Support, N.I.H., Extramural
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|a Research Support, Non-U.S. Gov't
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| 650 |
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|a Research Support, U.S. Gov't, Non-P.H.S.
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|a Arabidopsis
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| 650 |
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|a cadaverine
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|a natural variation
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|a polyamines
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|a roots
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|a transporter.
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| 650 |
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|a Arabidopsis Proteins
|2 NLM
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| 650 |
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|a Organic Cation Transporter 1
|2 NLM
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| 650 |
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|a Cadaverine
|2 NLM
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| 650 |
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|a L90BEN6OLL
|2 NLM
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| 700 |
1 |
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|a Vaughn, Laura M
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Masson, Patrick H
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 66(2015), 3 vom: 01. Feb., Seite 853-62
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnas
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| 773 |
1 |
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|g volume:66
|g year:2015
|g number:3
|g day:01
|g month:02
|g pages:853-62
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|u http://dx.doi.org/10.1093/jxb/eru444
|3 Volltext
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|a AR
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|d 66
|j 2015
|e 3
|b 01
|c 02
|h 853-62
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