High Density Lipoprotein Nanoparticles Deliver RNAi to Endothelial Cells to Inhibit Angiogenesis
Systemic delivery of therapeutic nucleic acids to target cells and tissues outside of the liver remains a major challenge. We synthesized a biomimetic high density lipoprotein nanoparticle (HDL NP) for delivery of a cholesteryl modified therapeutic nucleic acid (RNAi) to vascular endothelial cells,...
| Veröffentlicht in: | Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems. - 1999. - 31(2014), 11 vom: 01. Nov., Seite 1141-1150 |
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| Weitere Verfasser: | , , , |
| Format: | Aufsatz |
| Sprache: | English |
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2014
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| Zugriff auf das übergeordnete Werk: | Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems |
| Schlagworte: | Journal Article Angiogenesis HDL RNAi Tumor VEGFR2 |