Cholesterol drives aβ(1-42) interaction with lipid rafts in model membranes

The molecular mechanism at the basis of the neurodegenerative process related to Alzheimer's disease (AD) is triggered by the local composition of the neural plasma membrane. The role of cholesterol is controversial. In this investigation the interaction of the AD peptide amyloid-beta (1-42) wi...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 30(2014), 46 vom: 25. Nov., Seite 13934-41
1. Verfasser: Seghezza, Silvia (VerfasserIn)
Weitere Verfasser: Diaspro, Alberto, Canale, Claudio, Dante, Silvia
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Amyloid beta-Peptides Lipid Bilayers Peptide Fragments Phospholipids Sphingomyelins amyloid beta-protein (1-42) Cholesterol 97C5T2UQ7J