|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM243078064 |
| 003 |
DE-627 |
| 005 |
20231224131749.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231224s2014 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1021/la502343c
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n0810.xml
|
| 035 |
|
|
|a (DE-627)NLM243078064
|
| 035 |
|
|
|a (NLM)25347292
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Zou, Wen
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Surface modification of poly(ether sulfone) membrane with a synthesized negatively charged copolymer
|
| 264 |
|
1 |
|c 2014
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 13.07.2015
|
| 500 |
|
|
|a Date Revised 18.11.2014
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a In this study, we provide a new method to modify poly(ether sulfone) (PES) membrane with good biocompatibility, for which diazotized PES (PES-N2(+)) membrane is covalently coated by a negatively charged copolymer of sodium sulfonated poly(styrene-alt-maleic anhydride) (NaSPS-MA). First, aminated PES (PES-NH2) is synthesized by nitro reduction reaction of nitro-PES (PES-NO2), and then blends with pristine PES to prepare PES/PES-NH2 membrane; then the membrane is treated with NaNO2 aqueous solution at acid condition; after surface diazo reaction, surface positively charged PES/PES-N2(+) membrane is prepared. Second, poly(styrene-alt-maleic anhydride) (PS-alt-MA) is synthesized, then sulfonated and treated by sodium hydroxide solution to obtain sodium sulfonated (PS-alt-MA) (NaSPS-MA). Finally, the negatively charged NaSPS-MA copolymer is coated onto the surface positively charged PES/PES-N2(+) membrane via electrostatic interaction; after UV-cross-linking, the linkage between the PES-N2(+) and NaSPS-MA changes to a covalent bond. The surface-modified PES membrane is characterized by FT-IR spectroscopy, X-ray photoelectron spectroscopy (XPS) analyses, and surface zeta potential analyses. The modified membrane exhibits good hemocompatibility and cytocompatibility, and the improved biocompatibility might have resulted from the existence of the hydrophilic groups (sodium carboxylate (-COONa) and sodium sulfonate (-SO3Na)). Moreover, the stability of the modified membrane is also investigated. The results indicated that the modified PES membrane using negatively charged copolymers had a lot of potential in blood purification fields and bioartificial liver supports for a long time
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
7 |
|a Biocompatible Materials
|2 NLM
|
| 650 |
|
7 |
|a Maleates
|2 NLM
|
| 650 |
|
7 |
|a Polymers
|2 NLM
|
| 650 |
|
7 |
|a Polystyrenes
|2 NLM
|
| 650 |
|
7 |
|a Sulfones
|2 NLM
|
| 650 |
|
7 |
|a poly(styrene-alt-maleic anhydride)
|2 NLM
|
| 650 |
|
7 |
|a polyether sulfone
|2 NLM
|
| 650 |
|
7 |
|a 25667-42-9
|2 NLM
|
| 700 |
1 |
|
|a Qin, Hui
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Shi, Wenbin
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Sun, Shudong
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhao, Changsheng
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 30(2014), 45 vom: 18. Nov., Seite 13622-30
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
|
| 773 |
1 |
8 |
|g volume:30
|g year:2014
|g number:45
|g day:18
|g month:11
|g pages:13622-30
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1021/la502343c
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_22
|
| 912 |
|
|
|a GBV_ILN_350
|
| 912 |
|
|
|a GBV_ILN_721
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 30
|j 2014
|e 45
|b 18
|c 11
|h 13622-30
|