Abeta(1-42) enhances neuronal excitability in the CA1 via NR2B subunit-containing NMDA receptors
Neuronal hyperexcitability is a phenomenon associated with early Alzheimer's disease. The underlying mechanism is considered to involve excessive activation of glutamate receptors; however, the exact molecular pathway remains to be determined. Extracellular recording from the CA1 of hippocampal...
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Bibliographische Detailangaben
| Veröffentlicht in: | Neural plasticity. - 1998. - 2014(2014) vom: 13., Seite 584314
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| 1. Verfasser: |
Varga, Edina
(VerfasserIn) |
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| Weitere Verfasser: |
Juhász, Gábor,
Bozsó, Zsolt,
Penke, Botond,
Fülöp, Lívia,
Szegedi, Viktor |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2014
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| Zugriff auf das übergeordnete Werk: | Neural plasticity
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Amyloid beta-Peptides
NR2B NMDA receptor
Peptide Fragments
Receptors, AMPA
Receptors, N-Methyl-D-Aspartate
amyloid beta-protein (1-42) |
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