Multicentric epitheliotropic T-cell lymphoma in an African hedgehog (Atelerix albiventris)

© 2014 American Society for Veterinary Clinical Pathology.

Bibliographische Detailangaben
Veröffentlicht in:Veterinary clinical pathology. - 1975. - 43(2014), 4 vom: 01. Dez., Seite 601-4
1. Verfasser: Chung, Tae-Ho (VerfasserIn)
Weitere Verfasser: Kim, Hyo-Jin, Choi, Ul-Soo
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Veterinary clinical pathology
Schlagworte:Case Reports Journal Article Research Support, Non-U.S. Gov't Atelerix albiventris CD3 CD79a T-lymphocytes dermatosis neoplasia
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520 |a A 2-year-old female African hedgehog was presented with a 5-month history of pruritus, and diffuse spine and hair loss. A dermatologic examination revealed erythema, excoriation, scales, and crusting affecting the face, flanks, forelimbs, hindlimbs, and dorsal and ventral abdomen. Fine-needle aspiration was performed and skin biopsies were taken from several lesions for cytologic and histologic evaluation. The aspirates yielded smears characterized by a monomorphic population of medium-sized to large lymphocytes with scant to moderate amounts of clear to moderately basophilic cytoplasm and distinct nucleoli along with a low number of cytoplasmic fragments. On histopathologic examination, there were dense dermal lymphoid infiltrates invading the dermis and a monomorphic population of round cells that had infiltrated the overlying epidermis. Epitheliotropic cutaneous lymphoma was diagnosed based on morphologic features. Additional immunochemical analysis using anti-CD3 and anti-CD79a antibodies revealed strong CD3 expression by the tumor cells, which confirmed epitheliotropic cutaneous T-cell lymphoma. This is the first description of a multicentric pattern of epitheliotropic cutaneous T-cell lymphoma in an African hedgehog 
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700 1 |a Kim, Hyo-Jin  |e verfasserin  |4 aut 
700 1 |a Choi, Ul-Soo  |e verfasserin  |4 aut 
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