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20231224124410.0 |
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231224s2014 xx |||||o 00| ||eng c |
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7 |
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|a 10.1016/j.clim.2014.08.009
|2 doi
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|a pubmed24n0805.xml
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|a (DE-627)NLM241501962
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|a (NLM)25178982
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|a (PII)S1521-6616(14)00200-9
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|a DE-627
|b ger
|c DE-627
|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Shen, Long
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Evaluation of salivary gland protein 1 antibodies in patients with primary and secondary Sjogren's syndrome
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| 264 |
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1 |
|c 2014
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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| 500 |
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|a Date Completed 26.01.2015
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| 500 |
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|a Date Revised 31.03.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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| 520 |
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|a Copyright © 2014 Elsevier Inc. All rights reserved.
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|a Sjogren's syndrome (SS) has been associated with the expression of anti-Ro and anti-La antibodies. Anti-salivary gland protein 1 (SP1) antibodies have recently been identified in patients with SS. The current work involved a cross sectional study to determine whether anti-SP1 antibodies were identified in particular subgroups of patients with SS. The results of this study revealed that anti-SP1 antibodies were present in the sera of 52% of SS patients while anti-Ro/anti-La was present in 63% of patients. 19% of patients had anti-SP1 without anti-Ro/anti-La. Patients with SS and lymphoma expressed anti-Ro, anti-La and anti-SP1 together. In SS associated with RA, 50% had antibodies anti-SP1 while 40% had anti-Ro/anti-La. In conclusion, anti-SP1 antibodies are commonly seen in both primary and secondary SS and rarely in normal controls. Future studies are needed to determine the roles and timing of expression of anti-SP1 antibodies in Sjogren's syndrome
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| 650 |
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4 |
|a Journal Article
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4 |
|a Anti-La;
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| 650 |
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4 |
|a Anti-Ro;
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| 650 |
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4 |
|a Anti-salivary gland protein 1 (SP1)
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| 650 |
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4 |
|a Rheumatoid arthritis;
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| 650 |
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4 |
|a Sjogren's syndrome;
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| 650 |
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7 |
|a Autoantibodies
|2 NLM
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| 650 |
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7 |
|a Salivary Proteins and Peptides
|2 NLM
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| 700 |
1 |
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|a Kapsogeorgou, Efstathia K
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yu, Meixing
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Suresh, Lakshmanan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Malyavantham, Kishore
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Tzioufas, Anthanasios G
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ambrus, Julian L
|c Jr
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 155(2014), 1 vom: 12. Nov., Seite 42-46
|w (DE-627)NLM098196855
|x 1521-7035
|7 nnns
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| 773 |
1 |
8 |
|g volume:155
|g year:2014
|g number:1
|g day:12
|g month:11
|g pages:42-46
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| 856 |
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|u http://dx.doi.org/10.1016/j.clim.2014.08.009
|3 Volltext
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