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231224s2014 xx |||||o 00| ||eng c |
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|a 10.1021/la502705g
|2 doi
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|a pubmed24n0804.xml
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|a DE-627
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|e rakwb
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|a eng
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|a Gong, Ningqiang
|e verfasserin
|4 aut
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|a Microwave-assisted polyol synthesis of gadolinium-doped green luminescent carbon dots as a bimodal nanoprobe
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|c 2014
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 22.02.2016
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|a Date Revised 16.09.2014
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a The development of multimodal nanoprobes is highly desired in medical imaging because it integrates the advantages of multiple imaging modes. In this study, the gadolinium-doped green luminescent carbon dots (Gd-CDs) were prepared by the simple one-step microwave-assisted polyol method. The obtained Gd-CDs emitted a unique green photoluminescence with a quantum yield of 5.4%. The Gd-CDs exhibited a low cytotoxicity and could optically label the C6 glioma cells. Meanwhile, the r1 relaxivity of Gd-CDs was measured to be 11.356 mM(-1) s(-1). This high r1 value together with the r2/r1 ratio close to 1 nominates Gd-CDs as an excellent T1 contrast agent for magnetic resonance imaging. These Gd-CDs combining two complementary imaging modalities are therefore a promising bimodal nanoprobe in medical imaging for a better diagnosis
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Fluorescent Dyes
|2 NLM
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|a Polymers
|2 NLM
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|a polyol
|2 NLM
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|a Carbon
|2 NLM
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|a 7440-44-0
|2 NLM
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|a Gadolinium
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|a AU0V1LM3JT
|2 NLM
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|a Wang, Hao
|e verfasserin
|4 aut
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|a Li, Shuai
|e verfasserin
|4 aut
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|a Deng, Yunlong
|e verfasserin
|4 aut
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|a Chen, Xiao'ai
|e verfasserin
|4 aut
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|a Ye, Ling
|e verfasserin
|4 aut
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|a Gu, Wei
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 30(2014), 36 vom: 16. Sept., Seite 10933-9
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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|g volume:30
|g year:2014
|g number:36
|g day:16
|g month:09
|g pages:10933-9
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|u http://dx.doi.org/10.1021/la502705g
|3 Volltext
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