The Signaling Mechanism of TGF-β1 Induced Bovine Mammary Epithelial Cell Apoptosis

The present study showed that Transforming growth factor beta 1 (TGF-β1) can induce apoptosis of bovine mammary epithelial cells. This apoptosis was also observed with phosphorylation of Smad2/3 within 0.5-2 h. Afterwards the signal transferred into the nucleus. Moreover, intracellular free Ca(2+) c...

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Publié dans:Asian-Australasian journal of animal sciences. - 1998. - 25(2012), 3 vom: 24. März, Seite 304-10
Auteur principal: Di, He-Shuang (Auteur)
Autres auteurs: Wang, Li-Gang, Wang, Gen-Lin, Zhou, Lei, Yang, Yuan-Yuan
Format: Article en ligne
Langue:English
Publié: 2012
Accès à la collection:Asian-Australasian journal of animal sciences
Sujets:Journal Article ALK-5 Mammary Epithelial Cell TGF-β1 [Ca2+]i p-Smad2/3