Molecular dynamics simulations of self-emulsifying drug-delivery systems (SEDDS) : influence of excipients on droplet nanostructure and drug localization

In this study, molecular dynamics (MD) simulations were applied to model the lipidic nanoscale droplets that form when self-emulsifying drug-delivery systems (SEDDS) disperse into microemulsions in the gastrointestinal (GI) tract. The influence of the excipient composition on the droplet nanostructu...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 30(2014), 28 vom: 22. Juli, Seite 8471-80
1. Verfasser: Benson, Sven P (VerfasserIn)
Weitere Verfasser: Pleiss, Jürgen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Emulsions Excipients Surface-Active Agents