Polymeric supra-amphiphiles based on terminal group electrostatic interactions : fabrication of micelles with modifiable surfaces

On the basis of terminal group electrostatic interactions (TGEI), a supra-amphiphile is formed between a homopolymer of polylactic acid with carboxyl group at one end (PLA-COOH) and hepta-6-hydrazyl-β-cyclodextrin (HH-CD). The amphiphile can self-assemble into a micellar structure in aqueous solutio...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 30(2014), 29 vom: 29. Juli, Seite 8938-44
1. Verfasser: Liu, Zhi (VerfasserIn)
Weitere Verfasser: Qiao, Jing, Tian, Ye, Wu, Man, Niu, Zhongwei, Huang, Yong
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents Drug Carriers Micelles Polyesters Polymers Solutions Surface-Active Agents beta-Cyclodextrins mehr... Water 059QF0KO0R Lactic Acid 33X04XA5AT poly(lactide) 459TN2L5F5 Doxorubicin 80168379AG
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520 |a On the basis of terminal group electrostatic interactions (TGEI), a supra-amphiphile is formed between a homopolymer of polylactic acid with carboxyl group at one end (PLA-COOH) and hepta-6-hydrazyl-β-cyclodextrin (HH-CD). The amphiphile can self-assemble into a micellar structure in aqueous solution. The outer surface of the micelle, which is composed of cyclodextrins, can be further modified via host-guest interactions. Considering the biocompatibility of the building blocks, the application of the micelles in a nanocarrier of anticancer drugs is further explored 
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700 1 |a Qiao, Jing  |e verfasserin  |4 aut 
700 1 |a Tian, Ye  |e verfasserin  |4 aut 
700 1 |a Wu, Man  |e verfasserin  |4 aut 
700 1 |a Niu, Zhongwei  |e verfasserin  |4 aut 
700 1 |a Huang, Yong  |e verfasserin  |4 aut 
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