BACE1 is necessary for experience-dependent homeostatic synaptic plasticity in visual cortex

Alzheimer's disease (AD) is the most common form of age-related dementia, which is thought to result from overproduction and/or reduced clearance of amyloid-beta (Aβ) peptides. Studies over the past few decades suggest that Aβ is produced in an activity-dependent manner and has physiological re...

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Veröffentlicht in:Neural plasticity. - 1998. - 2014(2014) vom: 01., Seite 128631
1. Verfasser: Petrus, Emily (VerfasserIn)
Weitere Verfasser: Lee, Hey-Kyoung
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Neural plasticity
Schlagworte:Journal Article Research Support, N.I.H., Extramural Cytoskeletal Proteins Nerve Tissue Proteins activity regulated cytoskeletal-associated protein Amyloid Precursor Protein Secretases EC 3.4.- Aspartic Acid Endopeptidases EC 3.4.23.- Bace1 protein, mouse EC 3.4.23.46