Redox-responsive nanocarrier based on heparin end-capped mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo

This study reports a smart controlled drug release system based on mesoporous silica nanoparticles (MSNs) for targeted drug delivery. The system was fabricated by employing heparin as an end-capping agent to seal the mesopores of MSNs via disulfide bonds as intermediate linkers for intracellular glu...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 30(2014), 26 vom: 08. Juli, Seite 7867-77
Auteur principal: Dai, Liangliang (Auteur)
Autres auteurs: Li, Jinghua, Zhang, Beilu, Liu, Junjie, Luo, Zhong, Cai, Kaiyong
Format: Article en ligne
Langue:English
Publié: 2014
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents Drug Carriers Silicon Dioxide 7631-86-9 Doxorubicin 80168379AG