Redox-responsive nanocarrier based on heparin end-capped mesoporous silica nanoparticles for targeted tumor therapy in vitro and in vivo
This study reports a smart controlled drug release system based on mesoporous silica nanoparticles (MSNs) for targeted drug delivery. The system was fabricated by employing heparin as an end-capping agent to seal the mesopores of MSNs via disulfide bonds as intermediate linkers for intracellular glu...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 30(2014), 26 vom: 08. Juli, Seite 7867-77
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| 1. Verfasser: |
Dai, Liangliang
(VerfasserIn) |
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| Weitere Verfasser: |
Li, Jinghua,
Zhang, Beilu,
Liu, Junjie,
Luo, Zhong,
Cai, Kaiyong |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2014
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Antineoplastic Agents
Drug Carriers
Silicon Dioxide
7631-86-9
Doxorubicin
80168379AG |
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