Accuracy of cytology in distinguishing adrenocortical tumors from pheochromocytoma in companion animals

© 2014 American Society for Veterinary Clinical Pathology and European Society for Veterinary Clinical Pathology.

Bibliographische Detailangaben
Veröffentlicht in:Veterinary clinical pathology. - 1975. - 43(2014), 3 vom: 14. Sept., Seite 453-9
1. Verfasser: Bertazzolo, Walter (VerfasserIn)
Weitere Verfasser: Didier, Martine, Gelain, Maria Elena, Rossi, Silvia, Crippa, Luca, Avallone, Giancarlo, Roccabianca, Paola, Bonfanti, Ugo, Giori, Luca, Fracassi, Federico
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Veterinary clinical pathology
Schlagworte:Journal Article Cats Cushing disease dogs hyperadrenocorticism hyperaldosteronism
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500 |a Date Completed 12.06.2015 
500 |a Date Revised 31.03.2022 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a © 2014 American Society for Veterinary Clinical Pathology and European Society for Veterinary Clinical Pathology. 
520 |a BACKGROUND: The distinction between adrenocortical tumors and pheochromocytoma can be challenging using clinical findings, diagnostic imaging and laboratory tests. Cytology might be a simple, minimally invasive method to reach a correct diagnosis 
520 |a OBJECTIVES: The purpose of this study was to assess the accuracy of cytology in differentiating cortical from medullary tumors of the adrenal glands in dogs and cats 
520 |a METHODS: Cytologic key features of adrenocortical tumors and pheochromocytoma were defined by one reference author. Cytologic specimens from primary adrenal tumors were submitted to 4 cytopathologists who were asked to classify the tumors based on the previously defined key features without knowledge of previous classification 
520 |a RESULTS: Twenty specimens from histologically confirmed adrenal tumors (Group 1) and 4 specimens from adrenal tumors causing adrenal-dependent Cushing's syndrome (Group 2) were evaluated by the 4 cytopathologists. Accuracy in differentiating cortical from medullary origin ranged from 90% to 100%, with a Kappa coefficient of agreement between cytopathologists of 0.95 
520 |a CONCLUSIONS: The origin of an adrenal tumor can be easily determined by cytology alone in many cases. However, cytology was not reliable in distinguishing benign from malignant neoplasia. Additional studies are needed to assess possible risks and complications associated with fine-needle biopsy of adrenal tumors in dogs and cats 
650 4 |a Journal Article 
650 4 |a Cats 
650 4 |a Cushing disease 
650 4 |a dogs 
650 4 |a hyperadrenocorticism 
650 4 |a hyperaldosteronism 
700 1 |a Didier, Martine  |e verfasserin  |4 aut 
700 1 |a Gelain, Maria Elena  |e verfasserin  |4 aut 
700 1 |a Rossi, Silvia  |e verfasserin  |4 aut 
700 1 |a Crippa, Luca  |e verfasserin  |4 aut 
700 1 |a Avallone, Giancarlo  |e verfasserin  |4 aut 
700 1 |a Roccabianca, Paola  |e verfasserin  |4 aut 
700 1 |a Bonfanti, Ugo  |e verfasserin  |4 aut 
700 1 |a Giori, Luca  |e verfasserin  |4 aut 
700 1 |a Fracassi, Federico  |e verfasserin  |4 aut 
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773 1 8 |g volume:43  |g year:2014  |g number:3  |g day:14  |g month:09  |g pages:453-9 
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