Understanding the colloidal stability of the mesoporous MIL-100(Fe) nanoparticles in physiological media

The colloidal and chemical stability of nanoparticles of the nontoxic and biodegradable iron(III) trimesate MIL-100(Fe) nanocarrier have been evaluated in the presence of a series of simulated physiological fluids for intravenous and oral administration. MIL-100(Fe) nanoparticles exhibit an appropri...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 30(2014), 20 vom: 27. Mai, Seite 5911-20
1. Verfasser: Bellido, Elena (VerfasserIn)
Weitere Verfasser: Guillevic, Mazheva, Hidalgo, Tania, Santander-Ortega, Manuel J, Serre, Christian, Horcajada, Patricia
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Colloids Drug Carriers Tricarboxylic Acids Iron E1UOL152H7 trimesic acid OU36OO5MTN
Beschreibung
Zusammenfassung:The colloidal and chemical stability of nanoparticles of the nontoxic and biodegradable iron(III) trimesate MIL-100(Fe) nanocarrier have been evaluated in the presence of a series of simulated physiological fluids for intravenous and oral administration. MIL-100(Fe) nanoparticles exhibit an appropriate colloidal stability and biodegradability, mainly dependent on both the nature of their physicochemical surface and the media composition, being a priori compatible with their biomedical use
Beschreibung:Date Completed 13.04.2015
Date Revised 27.05.2014
published: Print-Electronic
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/la5012555