25th anniversary article : Rational design and applications of hydrogels in regenerative medicine

Hydrogels are hydrophilic polymer-based materials with high water content and physical characteristics that resemble the native extracellular matrix. Because of their remarkable properties, hydrogel systems are used for a wide range of biomedical applications, such as three-dimensional (3D) matrices...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 26(2014), 1 vom: 08. Jan., Seite 85-123
1. Verfasser: Annabi, Nasim (VerfasserIn)
Weitere Verfasser: Tamayol, Ali, Uquillas, Jorge Alfredo, Akbari, Mohsen, Bertassoni, Luiz E, Cha, Chaenyung, Camci-Unal, Gulden, Dokmeci, Mehmet R, Peppas, Nicholas A, Khademhosseini, Ali
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Review Elastomers Hydrogels
LEADER 01000caa a22002652 4500
001 NLM237452871
003 DE-627
005 20240610233715.0
007 cr uuu---uuuuu
008 231224s2014 xx |||||o 00| ||eng c
028 5 2 |a pubmed24n1435.xml 
035 |a (DE-627)NLM237452871 
035 |a (NLM)24741694 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Annabi, Nasim  |e verfasserin  |4 aut 
245 1 0 |a 25th anniversary article  |b Rational design and applications of hydrogels in regenerative medicine 
264 1 |c 2014 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 13.11.2014 
500 |a Date Revised 10.06.2024 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a Hydrogels are hydrophilic polymer-based materials with high water content and physical characteristics that resemble the native extracellular matrix. Because of their remarkable properties, hydrogel systems are used for a wide range of biomedical applications, such as three-dimensional (3D) matrices for tissue engineering, drug-delivery vehicles, composite biomaterials, and as injectable fillers in minimally invasive surgeries. In addition, the rational design of hydrogels with controlled physical and biological properties can be used to modulate cellular functionality and tissue morphogenesis. Here, the development of advanced hydrogels with tunable physiochemical properties is highlighted, with particular emphasis on elastomeric, light-sensitive, composite, and shape-memory hydrogels. Emerging technologies developed over the past decade to control hydrogel architecture are also discussed and a number of potential applications and challenges in the utilization of hydrogels in regenerative medicine are reviewed. It is anticipated that the continued development of sophisticated hydrogels will result in clinical applications that will improve patient care and quality of life 
650 4 |a Journal Article 
650 4 |a Research Support, N.I.H., Extramural 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Research Support, U.S. Gov't, Non-P.H.S. 
650 4 |a Review 
650 7 |a Elastomers  |2 NLM 
650 7 |a Hydrogels  |2 NLM 
700 1 |a Tamayol, Ali  |e verfasserin  |4 aut 
700 1 |a Uquillas, Jorge Alfredo  |e verfasserin  |4 aut 
700 1 |a Akbari, Mohsen  |e verfasserin  |4 aut 
700 1 |a Bertassoni, Luiz E  |e verfasserin  |4 aut 
700 1 |a Cha, Chaenyung  |e verfasserin  |4 aut 
700 1 |a Camci-Unal, Gulden  |e verfasserin  |4 aut 
700 1 |a Dokmeci, Mehmet R  |e verfasserin  |4 aut 
700 1 |a Peppas, Nicholas A  |e verfasserin  |4 aut 
700 1 |a Khademhosseini, Ali  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Advanced materials (Deerfield Beach, Fla.)  |d 1998  |g 26(2014), 1 vom: 08. Jan., Seite 85-123  |w (DE-627)NLM098206397  |x 1521-4095  |7 nnns 
773 1 8 |g volume:26  |g year:2014  |g number:1  |g day:08  |g month:01  |g pages:85-123 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 26  |j 2014  |e 1  |b 08  |c 01  |h 85-123