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231224s2014 xx |||||o 00| ||eng c |
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|a 10.1002/adma.201400953
|2 doi
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|a pubmed24n0791.xml
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|a (NLM)24737409
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|a DE-627
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|e rakwb
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|a eng
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|a Zhang, Hongbo
|e verfasserin
|4 aut
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| 245 |
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|a Fabrication of a multifunctional nano-in-micro drug delivery platform by microfluidic templated encapsulation of porous silicon in polymer matrix
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|c 2014
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 12.05.2015
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|a Date Revised 29.01.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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|a A multifunctional nano-in-micro drug delivery platform is developed by conjugating the porous silicon nanoparticles with mucoadhesive polymers and subsequent encapsulation into a pH-responsive polymer using microfluidics. The multistage platform shows monodisperse size distribution and pH-responsive payload release, and the released nanoparticles are mucoadhesive. Moreover, this platform is capable of simultaneously loading and releasing multidrugs with distinct properties
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a colon targeted drug delivery
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|a microfluidics
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|a mucoadhesion
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|a pH-responsive microcomposite
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|a porous silicon
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|a Polymers
|2 NLM
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|a Silicon
|2 NLM
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| 650 |
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|a Z4152N8IUI
|2 NLM
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| 700 |
1 |
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|a Liu, Dongfei
|e verfasserin
|4 aut
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1 |
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|a Shahbazi, Mohammad-Ali
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Mäkilä, Ermei
|e verfasserin
|4 aut
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|a Herranz-Blanco, Bárbara
|e verfasserin
|4 aut
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|a Salonen, Jarno
|e verfasserin
|4 aut
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|a Hirvonen, Jouni
|e verfasserin
|4 aut
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| 700 |
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|a Santos, Hélder A
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 26(2014), 26 vom: 09. Juli, Seite 4497-503
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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| 773 |
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|g volume:26
|g year:2014
|g number:26
|g day:09
|g month:07
|g pages:4497-503
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