Domain formation and permeabilization induced by the saponin α-hederin and its aglycone hederagenin in a cholesterol-containing bilayer

Saponins and triterpenic acids have been shown to be able to interact with lipid membranes and domains enriched with cholesterol (rafts). How saponins are able to modulate lipid phase separation in membranes and the role of the sugar chains for this activity is unknown. We demonstrate in a binary me...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1999. - 30(2014), 16 vom: 29. Apr., Seite 4556-69
1. Verfasser: Lorent, Joseph (VerfasserIn)
Weitere Verfasser: Lins, Laurence, Domenech, Òscar, Quetin-Leclercq, Joelle, Brasseur, Robert, Mingeot-Leclercq, Marie-Paule
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Lipid Bilayers Saponins beta-hederin Oleanolic Acid 6SMK8R7TGJ Cholesterol 97C5T2UQ7J hederagenin RQF57J8212