Mechanism of macromolecular structure evolution in self-assembled lipid nanoparticles for siRNA delivery
Lipid nanoparticles (LNPs) are a leading platform for therapeutic delivery of small interfering RNAs (siRNAs). Optimization of LNPs as therapeutic products is enabled by the development of structure-activity relationships (SAR) linking LNP physiochemical and macromolecular properties to bioperforman...
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Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 30(2014), 16 vom: 29. Apr., Seite 4613-22
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| 1. Verfasser: |
Gindy, Marian E
(VerfasserIn) |
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| Weitere Verfasser: |
DiFelice, Katherine,
Kumar, Varun,
Prud'homme, Robert K,
Celano, Robert,
Haas, R Matthew,
Smith, Jeffrey S,
Boardman, David |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2014
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Lipids
RNA, Small Interfering |
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