Mechanical properties of self-assembled Fmoc-diphenylalanine molecular gels
We explore the phase diagram and mechanical properties of molecular gels produced from mixing water with a dimethyl sulfoxide (DMSO) solution of the aromatic dipeptide derivative fluorenylmethoxycarbonyl-diphenylalanine (Fmoc-FF). Highly soluble in DMSO, Fmoc-FF assembles into fibrous networks that...
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 30(2014), 15 vom: 22. Apr., Seite 4493-500 |
|---|---|
| 1. Verfasser: | |
| Weitere Verfasser: | |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2014
|
| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids |
| Schlagworte: | Journal Article Research Support, U.S. Gov't, Non-P.H.S. Dipeptides Fluorenes Gels phenylalanylphenylalanine 2577-40-4 Phenylalanine 47E5O17Y3R Dimethyl Sulfoxide |
| Zusammenfassung: | We explore the phase diagram and mechanical properties of molecular gels produced from mixing water with a dimethyl sulfoxide (DMSO) solution of the aromatic dipeptide derivative fluorenylmethoxycarbonyl-diphenylalanine (Fmoc-FF). Highly soluble in DMSO, Fmoc-FF assembles into fibrous networks that form gels upon addition of water. At high water concentrations, rigid gels can be formed at Fmoc-FF concentrations as low as 0.01 wt %. The conditions are established defining the Fmoc-FF and water concentrations at which gels are formed. Below the gel boundary, the solutions are clear and colorless and have long-term stability. Above the gel boundary, gels are formed with increasing rapidity with increasing water or Fmoc-FF concentrations. A systematic characterization of the effect of Fmoc-FF and water concentrations on the mechanical properties of the gels is presented, demonstrating that the elastic behavior of the gels follows a specific, robust scaling with Fmoc-FF volume fraction. Furthermore, we characterize the kinetics of gelation and demonstrate that these gels are reversible in the sense that they can be disrupted mechanically and rebuild strength over time |
|---|---|
| Beschreibung: | Date Completed 15.04.2015 Date Revised 03.12.2021 published: Print-Electronic Citation Status MEDLINE |
| ISSN: | 1520-5827 |
| DOI: | 10.1021/la500589f |