Multifunctional Fe5 C2 nanoparticles a targeted theranostic platform for magnetic resonance imaging and photoacoustic tomography-guided photothermal therapy

Multifunctional Fe5 C2 nanoparticles : a targeted theranostic platform for magnetic resonance imaging and photoacoustic tomography-guided photothermal therapy

© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 26(2014), 24 vom: 25. Juni, Seite 4114-20
1. Verfasser: Yu, Jing (VerfasserIn)
Weitere Verfasser: Yang, Ce, Li, Jingdingsha, Ding, Yichen, Zhang, Lei, Yousaf, Muhammad Zubair, Lin, Jian, Pang, Rui, Wei, Lanbin, Xu, Lili, Sheng, Fugeng, Li, Changhui, Li, Gongjie, Zhao, Lingyun, Hou, Yanglong
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't iron carbides magnetic resonance imaging multifunctional probes photoacoustic tomography photothermal therapy Carbon Compounds, Inorganic Iron Compounds iron carbide
Beschreibung
Zusammenfassung:© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Fe5 C2 NPs exhibit a high contrast in magnetic resonance imaging (MRI), superior photoacoustic tomography improvements, and efficient photothermal therapy (PTT) due to their unique core/shell structure, with a magnetic core and carbon shell. By conjugating a new class of affinity proteins (ZHER2:342), they can target to tumor cells with low cytotoxicity, and kill them through laser irritation. It is also possible to ablate tumors under guidance by MRI and PTT without noticeable side effects
Beschreibung:Date Completed 22.04.2015
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201305811