Temperature-driven switching of the catalytic activity of artificial glutathione peroxidase by the shape transition between the nanotubes and vesicle-like structures

Smart supramolecular nanoenzymes with temperature-driven switching property have been successfully constructed by the self-assembly of supra-amphiphiles formed by the cyclodextrin-based host-guest chemistry. The self-assembled nanostructures were catalyst-functionalized and thermosensitively-functio...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 30(2014), 14 vom: 15. Apr., Seite 4013-8
1. Verfasser: Wang, Liang (VerfasserIn)
Weitere Verfasser: Zou, Huixin, Dong, Zeyuan, Zhou, Lipeng, Li, Jiaxi, Luo, Quan, Zhu, Junyan, Xu, Jiayun, Liu, Junqiu
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Acrylic Resins Cyclodextrins poly-N-isopropylacrylamide 25189-55-3 Glutathione Peroxidase EC 1.11.1.9
LEADER 01000naa a22002652 4500
001 NLM23662363X
003 DE-627
005 20231224105942.0
007 cr uuu---uuuuu
008 231224s2014 xx |||||o 00| ||eng c
024 7 |a 10.1021/la5008236  |2 doi 
028 5 2 |a pubmed24n0788.xml 
035 |a (DE-627)NLM23662363X 
035 |a (NLM)24654792 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Wang, Liang  |e verfasserin  |4 aut 
245 1 0 |a Temperature-driven switching of the catalytic activity of artificial glutathione peroxidase by the shape transition between the nanotubes and vesicle-like structures 
264 1 |c 2014 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 10.04.2015 
500 |a Date Revised 15.04.2014 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a Smart supramolecular nanoenzymes with temperature-driven switching property have been successfully constructed by the self-assembly of supra-amphiphiles formed by the cyclodextrin-based host-guest chemistry. The self-assembled nanostructures were catalyst-functionalized and thermosensitively-functionalized through conveniently linking the catalytic center of glutathione peroxidase and thermosensitive polymer to the host cyclodextrin molecules.The ON-OFF switches for the peroxidase activity by reversible transformation of nanostructures from tube to sphere have been achieved through changing the temperature. We anticipate that such intelligent enzyme mimics could be developed to use in an antioxidant medicine with controlled catalytic efficiency according to the needs of the human body in the future 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 7 |a Acrylic Resins  |2 NLM 
650 7 |a Cyclodextrins  |2 NLM 
650 7 |a poly-N-isopropylacrylamide  |2 NLM 
650 7 |a 25189-55-3  |2 NLM 
650 7 |a Glutathione Peroxidase  |2 NLM 
650 7 |a EC 1.11.1.9  |2 NLM 
700 1 |a Zou, Huixin  |e verfasserin  |4 aut 
700 1 |a Dong, Zeyuan  |e verfasserin  |4 aut 
700 1 |a Zhou, Lipeng  |e verfasserin  |4 aut 
700 1 |a Li, Jiaxi  |e verfasserin  |4 aut 
700 1 |a Luo, Quan  |e verfasserin  |4 aut 
700 1 |a Zhu, Junyan  |e verfasserin  |4 aut 
700 1 |a Xu, Jiayun  |e verfasserin  |4 aut 
700 1 |a Liu, Junqiu  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Langmuir : the ACS journal of surfaces and colloids  |d 1992  |g 30(2014), 14 vom: 15. Apr., Seite 4013-8  |w (DE-627)NLM098181009  |x 1520-5827  |7 nnns 
773 1 8 |g volume:30  |g year:2014  |g number:14  |g day:15  |g month:04  |g pages:4013-8 
856 4 0 |u http://dx.doi.org/10.1021/la5008236  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_22 
912 |a GBV_ILN_350 
912 |a GBV_ILN_721 
951 |a AR 
952 |d 30  |j 2014  |e 14  |b 15  |c 04  |h 4013-8