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231224s2014 xx |||||o 00| ||eng c |
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7 |
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|a 10.3928/23258160-20140306-08
|2 doi
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5 |
2 |
|a pubmed25n0788.xml
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|a (NLM)24635156
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|e rakwb
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| 041 |
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|a eng
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| 100 |
1 |
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|a Fileta, John B
|e verfasserin
|4 aut
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| 245 |
1 |
0 |
|a Meta-analysis of infectious endophthalmitis after intravitreal injection of anti-vascular endothelial growth factor agents
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| 264 |
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1 |
|c 2014
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| 336 |
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 24.09.2014
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|a Date Revised 21.03.2022
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a Copyright 2014, SLACK Incorporated.
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|a BACKGROUND AND OBJECTIVE: To investigate the rate of endophthalmitis after intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents, the spectrum of causative organisms, and associated visual acuity outcomes
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| 520 |
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|a PATIENTS AND METHODS: PubMed articles containing the keywords "endophthalmitis" and "intravitreal" between January 2005 and May 2012 were identified and reviewed. Inclusion criteria included article in English, more than 100 intravitreal anti-VEGF injections, and report of adverse events including endophthalmitis after intravitreal injection
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| 520 |
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|a RESULTS: Forty-three articles were analyzed. Endophthalmitis occurred after 197 of 350,535 intravitreal anti-VEGF injections (0.056%). The most common organisms isolated were coagulase-negative Staphylococcus (38.24%) and Streptococcus species (29.41%)
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|a CONCLUSION: The reported rate of endophthalmitis after intravitreal anti-VEGF injection is low. Coagulase-negative Staphylococcus and Streptococcus species were the most frequent causative organisms. Streptococcus species represent the causative organism of endophthalmitis after intravitreal VEGF injections at a higher rate than rates reported in the literature for endophthalmitis following most incisional intraocular surgeries. Among patients with endophthalmitis after intravitreal anti-VEGF injection, endophthalmitis caused by Streptococcus species is associated with poorer visual acuity outcomes than endophthalmitis caused by coagulase-negative Staphylococcus and culture-negative cases
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|a Journal Article
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4 |
|a Meta-Analysis
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7 |
|a Angiogenesis Inhibitors
|2 NLM
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| 650 |
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7 |
|a VEGFA protein, human
|2 NLM
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| 650 |
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7 |
|a Vascular Endothelial Growth Factor A
|2 NLM
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| 700 |
1 |
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|a Scott, Ingrid U
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Flynn, Harry W
|c Jr
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Ophthalmic surgery, lasers & imaging retina
|d 2013
|g 45(2014), 2 vom: 07. März, Seite 143-9
|w (DE-627)NLM224956647
|x 2325-8179
|7 nnas
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| 773 |
1 |
8 |
|g volume:45
|g year:2014
|g number:2
|g day:07
|g month:03
|g pages:143-9
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4 |
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