Development of zwitterionic polymer-based doxorubicin conjugates : tuning the surface charge to prolong the circulation and reduce toxicity

Polymer-drug conjugates are commonly used as nano drug vehicles (NDVs) to delivery anticancer drugs. Zwitterionic polymers are ideal candidates to conjugate drugs because they show higher resistance to nonspecific protein adsorption in complex media than that of nonionic water-soluble polymers, such...

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Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1992. - 30(2014), 13 vom: 08. Apr., Seite 3764-74
1. Verfasser:	Wang, Zhen (VerfasserIn)
Weitere Verfasser:	Ma, Guanglong, Zhang, Juan, Lin, Weifeng, Ji, Fangqin, Bernards, Matthew T, Chen, Shengfu
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2014
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Antineoplastic Agents Drug Carriers Polymethacrylic Acids polycarboxybetaine methacrylate Betaine 3SCV180C9W Polyethylene Glycols 3WJQ0SDW1A mehr... Doxorubicin 80168379AG