Anchoring group effects of surface ligands on magnetic properties of Fe₃ O₄ nanoparticles : towards high performance MRI contrast agents
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publié dans: | Advanced materials (Deerfield Beach, Fla.). - 1998. - 26(2014), 17 vom: 08. Mai, Seite 2694-8, 2016 |
---|---|
Auteur principal: | |
Autres auteurs: | , , , , , , , , |
Format: | Article en ligne |
Langue: | English |
Publié: |
2014
|
Accès à la collection: | Advanced materials (Deerfield Beach, Fla.) |
Sujets: | Journal Article Research Support, Non-U.S. Gov't Fe3O4 nanoparticle MRI PEG ligand anchoring group contrast enhancement effect |
Résumé: | © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. The effect of the anchoring group of surface ligands on the magnetic properties, especially relaxometric properties, of PEGylated Fe₃ O₄ nanoparticles is investigated. Systematic experimental results together with in-depth theoretical analysis reveal that the ligand binding affinity can largely vary the saturation magnetization, whereas conjugated anchoring groups can remarkably enhance the transverse relaxivity, which highlights a novel approach for achieving high-performance MRI contrast agents |
---|---|
Description: | Date Completed 17.04.2015 Date Revised 01.10.2020 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
ISSN: | 1521-4095 |
DOI: | 10.1002/adma.201304744 |