Microfluidic-assisted self-assembly of complex dendritic polyethylene drug delivery nanocapsules

Microfluidic-assisted self-assembly of complex dendritic polyethylene drug delivery nanocapsules

© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 26(2014), 19 vom: 21. Mai, Seite 3118-23
1. Verfasser: Hasani-Sadrabadi, Mohammad Mahdi (VerfasserIn)
Weitere Verfasser: Karimkhani, Vahid, Majedi, Fatemeh Sadat, Van Dersarl, Jules John, Dashtimoghadam, Erfan, Afshar-Taromi, Faramarz, Mirzadeh, Hamid, Bertsch, Arnaud, Jacob, Karl I, Renaud, Philippe, Stadler, Florian J, Kim, Il
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2014
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't cancer therapeutics controlled drug delivery hyperbranched polyethylene nanocapsule microfluidic-assisted self-assembly paclitaxel Antineoplastic Agents, Phytogenic Dendrimers Nanocapsules mehr... Polyethylene 9002-88-4 Paclitaxel P88XT4IS4D
Beschreibung
Zusammenfassung:© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Microfluidic platform for the synthesis of complex nanocapsules is presented via a controlled self-assembly. The monodisperse nanocapsules in the range of 50-200 nm consist of a dendritic polyethylene core and a Pluronic copolymer shell. The resultant nanocarriers encapsulate large amount of hydrophobic anticancer drug like paclitaxel while providing a low complement activation as well as sustained release profile with high tunability
Beschreibung:Date Completed 20.04.2015
Date Revised 30.09.2020
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-4095
DOI:10.1002/adma.201305753