Carboplatin plus irinotecan induced partial response in a patient with small cell carcinoma of the prostate; a case report
An 80-year-old man with prostate cancer receiving hormone therapy presented with urinary retention. The computed tomographic scan showed metastases to the lung, liver, and lymph nodes, as well as increased prostate volume. Transurethral resection of the prostate (TURP) was performed, and the resecte...
| Veröffentlicht in: | Hinyokika kiyo. Acta urologica Japonica. - 1962. - 60(2014), 1 vom: 26. Jan., Seite 39-43 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , |
| Format: | Aufsatz |
| Sprache: | Japanese |
| Veröffentlicht: |
2014
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| Zugriff auf das übergeordnete Werk: | Hinyokika kiyo. Acta urologica Japonica |
| Schlagworte: | Case Reports Journal Article Review Biomarkers, Tumor Irinotecan 7673326042 Carboplatin BG3F62OND5 Phosphopyruvate Hydratase EC 4.2.1.11 mehr... |
| Zusammenfassung: | An 80-year-old man with prostate cancer receiving hormone therapy presented with urinary retention. The computed tomographic scan showed metastases to the lung, liver, and lymph nodes, as well as increased prostate volume. Transurethral resection of the prostate (TURP) was performed, and the resected specimen was pathologically found to be a small cell carcinoma of the prostate. The patient was treated with a combination of carboplatin and irinotecan, and achieved a partial response : size reduction of the prostate and the metastatic lesions, and decreased neuron specific enolase (NSE) level. The chemotherapy with carboplatin and irinotecan is reported to have fewer serious adverse effects, and equivalent efficacy to the cisplatin/etoposide chemotherapy. Therefore, this regimen could also be a treatment option for the patients with small cell carcinoma of the prostate |
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| Beschreibung: | Date Completed 13.05.2014 Date Revised 02.12.2018 published: Print Citation Status MEDLINE |
| ISSN: | 0018-1994 |